Step 1
Pharmacology sources
Every interaction rule starts from FDA Structured Product Labels, DailyMed monographs, peer-reviewed pharmacology, and dermatology consensus guidelines (AAD, AOCD). We never derive an interaction from a single source.
The BlendSafe methodology
How we check a combination against the label.
BlendSafe is an informational tool, not a diagnostic device. Here's the exact pipeline behind every verdict — sources, review process, severity tiers, and what we do when the literature disagrees.
Step 2
Clinical review
Every HIGH-risk interaction is reviewed and signed off by a licensed pharmacist before it's surfaced to users. MODERATE rows cite at least two independent sources. LOW rows are calibrated against routines real patients actually run.
Step 3
Severity tiering
Severity is recorded in two fields: a coarse `risk_level` (LOW / MODERATE / HIGH) used for routing, and a finer clinical `severity` (1–5) used for the headline verdict. Both are auditable in the admin moderation log.
Step 4
Continuous updates
The catalog refreshes weekly. New FDA labels, retracted studies, and clinician feedback all flow through the same review pipeline — no silent edits.
Important — not medical advice
BlendSafe is an informational tool. It does not replace a consultation with your dermatologist, OB-GYN, or pharmacist. If a verdict suggests AVOID for a product you depend on, talk to a clinician before making any change to your medication or routine.